https://www.explainxkcd.com/wiki/api.php?action=feedcontributions&feedformat=atom&user=Kdrangej 2026-04-17T07:53:23Z User contributions MediaWiki 1.30.0 https://www.explainxkcd.com/wiki/index.php?title=1430:_Proteins&diff=76752 2014-10-06T09:09:29Z

<p>Kdrangej: Added a comma</p> <hr /> <div>{{comic<br /> | number = 1430<br /> | date = October 6, 2014<br /> | title = Proteins<br /> | image = proteins.png<br /> | titletext = Check it out--when I tug the C-terminal tail, the binding tunnel squeezes!<br /> }}<br /> <br /> ==Explanation==<br /> {{incomplete|More info on protein folding, expansion on F@H, explanaiton of the joke and title text.}}<br /> <br /> {{w|Protein folding}} is a mechanism exhibited by protein structures to assume a functional shape. If the folding sequence does not complete, or completes incorrectly, the resulting protein can be inactive or even toxic to the body. These misfolded proteins are responsible for certain allergies, and are believed to be the cause of several {{w|neurodegenerative}} and other diseases.<br /> <br /> {{w|Folding@Home}} (F@H) is a distrubuted computing project which aims to simulate protein folding for research purposes. Rather than the traditional model of using a supercomputer for computation, the project uses idle processing power of a network of personal computers in order to achieve massive computing power. Individuals can join the project by installing the F@H software, and are then able to track their contribution to the project. Individual members may join together as a team, with leaderboards measuring team and individual contributions.<br /> <br /> In origami, purists [[http://www.barf.cc/jeremy/origami/BOOK/essays/origami_purism/origami_purism.htm]] considered it as cheating if you cut the paper or use more than one sheet of paper.<br /> <br /> ==Transcript==<br /> :[Cueball is talking with Megan]<br /> :Cueball: What do you do?<br /> :Megan: I make software that predicts how proteins will fold.<br /> :Cueball: Is that a hard problem?<br /> :Megan: Someone may someday find a harder one.<br /> :Cueball: Why is it so hard?<br /> :Megan: Have you ever made a folded paper crane?<br /> :Cueball: Yeah.<br /> :Megan: Imagine figuring out the folds to make an actual &lt;em&gt;living&lt;/em&gt; crane.<br /> :Cueball: ...&lt;em&gt;just&lt;/em&gt; folds? Can I make cuts?<br /> :Megan: If you can fold a protease enzyme.<br /> {{comic discussion}}</div>

Kdrangej https://www.explainxkcd.com/wiki/index.php?title=1430:_Proteins&diff=76751 2014-10-06T09:08:57Z

<p>Kdrangej: Added a little note about cutting the paper in origami</p> <hr /> <div>{{comic<br /> | number = 1430<br /> | date = October 6, 2014<br /> | title = Proteins<br /> | image = proteins.png<br /> | titletext = Check it out--when I tug the C-terminal tail, the binding tunnel squeezes!<br /> }}<br /> <br /> ==Explanation==<br /> {{incomplete|More info on protein folding, expansion on F@H, explanaiton of the joke and title text.}}<br /> <br /> {{w|Protein folding}} is a mechanism exhibited by protein structures to assume a functional shape. If the folding sequence does not complete, or completes incorrectly, the resulting protein can be inactive or even toxic to the body. These misfolded proteins are responsible for certain allergies, and are believed to be the cause of several {{w|neurodegenerative}} and other diseases.<br /> <br /> {{w|Folding@Home}} (F@H) is a distrubuted computing project which aims to simulate protein folding for research purposes. Rather than the traditional model of using a supercomputer for computation, the project uses idle processing power of a network of personal computers in order to achieve massive computing power. Individuals can join the project by installing the F@H software, and are then able to track their contribution to the project. Individual members may join together as a team, with leaderboards measuring team and individual contributions.<br /> <br /> In origami purists [[http://www.barf.cc/jeremy/origami/BOOK/essays/origami_purism/origami_purism.htm]] considered it as cheating if you cut the paper or use more than one sheet of paper.<br /> <br /> ==Transcript==<br /> :[Cueball is talking with Megan]<br /> :Cueball: What do you do?<br /> :Megan: I make software that predicts how proteins will fold.<br /> :Cueball: Is that a hard problem?<br /> :Megan: Someone may someday find a harder one.<br /> :Cueball: Why is it so hard?<br /> :Megan: Have you ever made a folded paper crane?<br /> :Cueball: Yeah.<br /> :Megan: Imagine figuring out the folds to make an actual &lt;em&gt;living&lt;/em&gt; crane.<br /> :Cueball: ...&lt;em&gt;just&lt;/em&gt; folds? Can I make cuts?<br /> :Megan: If you can fold a protease enzyme.<br /> {{comic discussion}}</div>

Kdrangej