Editing 2161: An Apple a Day

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[[Megan]] is giving a talk, starting with the common proverb, before continuing with "At least, it used to." In a normal scenario, this might have been to imply that eating apples is no longer enough to stay healthy. However, in this comic, this expression is reinterpreted to mean that an apple used to repel a doctor. It also suggests that keeping doctors away is of great importance, presumably because doctors in this scenario are undesirable. The method of action of apples is not specified; they could act as repellents, analogous to {{w|insect repellent}}, or possibly as lethal agents, as {{w|antibiotics}} are to {{w|bacteria}}, or {{w|fungicide|fungicides}} are to {{w|fungus|fungi}}.  
 
[[Megan]] is giving a talk, starting with the common proverb, before continuing with "At least, it used to." In a normal scenario, this might have been to imply that eating apples is no longer enough to stay healthy. However, in this comic, this expression is reinterpreted to mean that an apple used to repel a doctor. It also suggests that keeping doctors away is of great importance, presumably because doctors in this scenario are undesirable. The method of action of apples is not specified; they could act as repellents, analogous to {{w|insect repellent}}, or possibly as lethal agents, as {{w|antibiotics}} are to {{w|bacteria}}, or {{w|fungicide|fungicides}} are to {{w|fungus|fungi}}.  
  
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Megan continues with her reinterpretation, mentioning that doctors have become resistant to apples so two or even three may be needed. As control agents become more widely used, organisms which are less sensitive to the control may become more common, as is happening with [https://www.nature.com/news/2010/100503/full/news.2010.216.html mosquitoes becoming insensitive to repellents], or {{w|antimicrobial resistance}}, and {{w|pesticide resistance}}.  Such resistant organisms may require higher doses, or use of multiple control agents.  
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Megan continues with her reinterpretation, mentioning that doctors have become resistant to apples so two or even three may be needed. As control agents become more widely used, organisms which are less sensitive to the control may become more common, as is happening with mosquitoes becoming insensitive to repellents[https://www.nature.com/news/2010/100503/full/news.2010.216.html], or {{w|antimicrobial resistance}}, and {{w|pesticide resistance}}.  Such resistant organisms may require higher doses, or use of multiple control agents.  
  
 
In the worst cases, doctors have become completely immune to apples (i.e., {{w|superbugs}}). A poster behind Megan shows [[:Category:Doctor Ponytail|Doctor Ponytail]] with three apples above her. Megan advocates using the 'finest' apples only in these cases (a reference to {{w|Multiple drug resistance|multidrug-resistant}} {{w|pathogens}}, where some antibiotics are only used as a last-resort to reduce the development of resistance to them).
 
In the worst cases, doctors have become completely immune to apples (i.e., {{w|superbugs}}). A poster behind Megan shows [[:Category:Doctor Ponytail|Doctor Ponytail]] with three apples above her. Megan advocates using the 'finest' apples only in these cases (a reference to {{w|Multiple drug resistance|multidrug-resistant}} {{w|pathogens}}, where some antibiotics are only used as a last-resort to reduce the development of resistance to them).

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