This is not that weird. If names were random then it would be a 1 in 26^4 = 456976 chance of a particular president matching another for the first 4, but this is a "Birthday Problem" with 44 presidents, so the probability of any two presidents sharing the first 4 characters is 1-(456976!/(456976^44 (456976 - 44)!)), which wolfram alpha is giving as 0.206%
An approximation to the correct probability would be to do 44^2/(2 x 26^4) which would give about 0.2% chance of this happening. So fairly weird, but as the comic suggests, many things about this presidency are weirder than 0.2%.