Editing Talk:2283: Exa-Exabyte

Jump to: navigation, search
Ambox notice.png Please sign your posts with ~~~~

Warning: You are not logged in. Your IP address will be publicly visible if you make any edits. If you log in or create an account, your edits will be attributed to your username, along with other benefits.

The edit can be undone. Please check the comparison below to verify that this is what you want to do, and then save the changes below to finish undoing the edit.
Latest revision Your text
Line 6: Line 6:
 
::::Did someone already modified SARS-CoV-2 to be able to infect computers as well? -- [[User:Hkmaly|Hkmaly]] ([[User talk:Hkmaly|talk]]) 23:35, 20 March 2020 (UTC)
 
::::Did someone already modified SARS-CoV-2 to be able to infect computers as well? -- [[User:Hkmaly|Hkmaly]] ([[User talk:Hkmaly|talk]]) 23:35, 20 March 2020 (UTC)
 
:::::Hm, not that I can find... This looks like a job for xkcd readers! Somebody get right on this, please. [[User:ProphetZarquon|ProphetZarquon]] ([[User talk:ProphetZarquon|talk]]) 06:12, 21 March 2020 (UTC)
 
:::::Hm, not that I can find... This looks like a job for xkcd readers! Somebody get right on this, please. [[User:ProphetZarquon|ProphetZarquon]] ([[User talk:ProphetZarquon|talk]]) 06:12, 21 March 2020 (UTC)
::::::I also immediately thought of COVID19 when he started on biology. Of course is can be dabated if this comic has nothing to do with the vira, but it is still about how much life there is and big numbers. And he amount of vira in the world is a big number... Hard to imagine, just like exponential growth is hard for humans to understand. I'd say that if the next comic on Monday is again clearly on COVID19 then the strak did not end here, just took a detour around some aspect of biology related to the problems at hand. --[[User:Kynde|Kynde]] ([[User talk:Kynde|talk]]) 16:54, 21 March 2020 (UTC)
+
::::::I also immediately thought of COVIS19 when he started on biology. Of course is can be dabated if this comic has nothing to do with the vira, but it is still about how much life there is and big numbers. And he amount of vira in the world is a big number... Hard to imagine, just like exponential growth is hard for humans to understand. I'd say that if the next comic on Monday is again clearly on COVID19 then the strak did not end here, just took a detour around some aspect of biology related to the problems at hand. --[[User:Kynde|Kynde]] ([[User talk:Kynde|talk]]) 16:54, 21 March 2020 (UTC)
:::::::(...a job for xkcd readers...) I have a different idea: Rewrite the {{w|EICAR test file}} as an equivalently functional (R|D)NA package. Nothing can go wrong! [[Special:Contributions/162.158.92.98|162.158.92.98]] 19:35, 21 March 2020 (UTC)
+
::::::(...a job for xkcd readers...) I have a different idea: Rewrite the {{w|EICAR test file}} as an equivalently functional (R|D)NA package. Nothing can go wrong! [[Special:Contributions/162.158.92.98|162.158.92.98]] 19:35, 21 March 2020 (UTC)
::::::::The funny thing about the exa-exabyte calculation is that it vastly underestimates the actual information entropy of DNA. For example, it doesn't take into account [https://en.wikipedia.org/wiki/Epigenetics epigenetic modifications] (e.g. histone acetylation and DNA methylation) in [https://en.wikipedia.org/wiki/Eukaryote eukaryotes]. Interestingly, one reason why biologists can't get cloning to work is because simply copying the genome leaves behind epigenetic modifications (the "epigenome") that are critical to proper development and normally passed down through inheritance. In addition, most of the human genome doesn't even code for proteins (which is what people usually think of in terms of the information DNA encodes). Some of the genome encodes RNAs like [https://en.wikipedia.org/wiki/Piwi-interacting_RNA piwi-interacting RNA], which function in RNA silencing and epigenetic effects and probably other things biologists don't even know about yet. Even weirder are [https://en.wikipedia.org/wiki/Transposable_element transposons], which are mobile DNA sequences that jump around in the genome and can cause mutations and such. Biology is full of feedback loops, so stuff like epigenetic modification will affect the 3D structure of DNA, which can affect gene expression, which can affect epigenetic modification, and it's turtles all the way down. This is the messy [https://en.wikipedia.org/wiki/Schistocyte schistocyte] you get when evolution programs an organism's code. Simply counting DNA bases only hints at the true complexity of biology. BTW, HCoV-19 (human coronavirus 2019, another name for SARS-CoV-2 that I prefer because it avoids confusion with the 2003 SARS pandemic) happens to use RNA instead of DNA for its genome, for some reason. ¯\_(ツ)_/¯ --[[User:In vivo veritas|In vivo veritas]] ([[User talk:In vivo veritas|talk]]) 05:15, 22 March 2020 (UTC)
+
:::::::The funny thing about the exa-exabyte calculation is that it vastly underestimates the actual information entropy of DNA. For example, it doesn't take into account [https://en.wikipedia.org/wiki/Epigenetics epigenetic modifications] (e.g. histone acetylation and DNA methylation) in [https://en.wikipedia.org/wiki/Eukaryote eukaryotes]. Interestingly, one reason why biologists can't get cloning to work is because simply copying the genome leaves behind epigenetic modifications (the "epigenome") that are critical to proper development and normally passed down through inheritance. In addition, most of the human genome doesn't even code for proteins (which is what people usually think of in terms of the information DNA encodes). Some of the genome encodes RNAs like [https://en.wikipedia.org/wiki/Piwi-interacting_RNA piwi-interacting RNA], which function in RNA silencing and epigenetic effects and probably other things biologists don't even know about yet. Even weirder are [https://en.wikipedia.org/wiki/Transposable_element transposons], which are mobile DNA sequences that jump around in the genome and can cause mutations and such. Biology is full of feedback loops, so stuff like epigenetic modification will affect the 3D structure of DNA, which can affect gene expression, which can affect epigenetic modification, and it's turtles all the way down. This is the messy [https://en.wikipedia.org/wiki/Schistocyte schistocyte] you get when evolution programs an organism's code. Simply counting DNA bases only hints at the true complexity of biology. BTW, HCoV-19 (human coronavirus 2019, another name for SARS-CoV-2 that I prefer because it avoids confusion with the 2003 SARS pandemic) happens to use RNA instead of DNA for its genome, for some reason. ¯\_(ツ)_/¯ --[[User:In vivo veritas|In vivo veritas]] ([[User talk:In vivo veritas|talk]]) 05:15, 22 March 2020 (UTC)
  
 
So,  is she counting all of humanity as one string of DNA data,  or does each human count separately,  or each cell in a human's body,  or what?
 
So,  is she counting all of humanity as one string of DNA data,  or does each human count separately,  or each cell in a human's body,  or what?

Please note that all contributions to explain xkcd may be edited, altered, or removed by other contributors. If you do not want your writing to be edited mercilessly, then do not submit it here.
You are also promising us that you wrote this yourself, or copied it from a public domain or similar free resource (see explain xkcd:Copyrights for details). Do not submit copyrighted work without permission!

To protect the wiki against automated edit spam, we kindly ask you to solve the following CAPTCHA:

Cancel | Editing help (opens in new window)

Template used on this page: