Difference between revisions of "Talk:2530: Clinical Trials"
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I would say this in relation to the mutiple treatments for Covid19 some of which have great clinical evaluation, others less so. I'll make a first draft [[User:Kev|Kev]] ([[User talk:Kev|talk]]) 21:53, 18 October 2021 (UTC) | I would say this in relation to the mutiple treatments for Covid19 some of which have great clinical evaluation, others less so. I'll make a first draft [[User:Kev|Kev]] ([[User talk:Kev|talk]]) 21:53, 18 October 2021 (UTC) | ||
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| + | Note that a proper clinical trial does not "prove" its treatment to be effective, but it actually should do its damnedest to show that any observed (net) benefits are down to simple statistical fluke, but then fail, leaving the positive result 'proven'. And obviously extract every possible risk factor in the process. (Thalidomide fell down badly on this, many years ago, partly because of the numbers involved and the fact that susceptible mothers were often taking a cocktail of multiple 'remedies' over much of the nine months, which made the reality slow to be teased out. But the lessons learnt mean that authorising ''anything'' for pregnant women are tortuous, and testing on (non-pregnant) women in general is hampered by having to account for menstral cycles, so we end up with far too many man-tested drugs that say "not for use in pregnancy" just to keep far to the safe-side, plus still far more unknown levels of efficacy/etc in the 'generic' female body than we should have. But it's being addressed. Onward, ever onward!) [[Special:Contributions/162.158.159.49|162.158.159.49]] 23:14, 18 October 2021 (UTC) | ||
Revision as of 23:14, 18 October 2021
Is this comic in reaction to some specific recent event? It seems like it might be related to vaccine trials, given the pandemic the world has been dealing with for the last 2 years... if so, it then seems to be a condemnation... am I reading too much into this? Ericfromabeno (talk) 21:49, 18 October 2021 (UTC)
I would say this in relation to the mutiple treatments for Covid19 some of which have great clinical evaluation, others less so. I'll make a first draft Kev (talk) 21:53, 18 October 2021 (UTC)
Note that a proper clinical trial does not "prove" its treatment to be effective, but it actually should do its damnedest to show that any observed (net) benefits are down to simple statistical fluke, but then fail, leaving the positive result 'proven'. And obviously extract every possible risk factor in the process. (Thalidomide fell down badly on this, many years ago, partly because of the numbers involved and the fact that susceptible mothers were often taking a cocktail of multiple 'remedies' over much of the nine months, which made the reality slow to be teased out. But the lessons learnt mean that authorising anything for pregnant women are tortuous, and testing on (non-pregnant) women in general is hampered by having to account for menstral cycles, so we end up with far too many man-tested drugs that say "not for use in pregnancy" just to keep far to the safe-side, plus still far more unknown levels of efficacy/etc in the 'generic' female body than we should have. But it's being addressed. Onward, ever onward!) 162.158.159.49 23:14, 18 October 2021 (UTC)
