Editing 1260: LD50

Jump to: navigation, search

Warning: You are not logged in. Your IP address will be publicly visible if you make any edits. If you log in or create an account, your edits will be attributed to your username, along with other benefits.

The edit can be undone. Please check the comparison below to verify that this is what you want to do, and then save the changes below to finish undoing the edit.
Latest revision Your text
Line 8: Line 8:
  
 
==Explanation==
 
==Explanation==
{{w|Median lethal dose|LD<sub>50</sub>}} is a term used in toxicology that identifies the median lethal dose of a toxin, or how much is required to kill 50% of a given population. LD<sub>50</sub>s are usually measured in g/kg, as the amount of toxin to kill something is usually linearly related to its mass. The lower the LD<sub>50</sub>, the more lethal the toxin. An LD<sub>50</sub> can be determined for almost any substance: for example, the LD<sub>50</sub> for sugar (in rats) is 29.7&nbsp;g/kg. However, {{w|Botulinum toxin}} (commercially known as Botox in the beauty industry), the most acutely toxic substance known, has a LD<sub>50</sub> of roughly 1&nbsp;ng/kg, or 0.000000001&nbsp;g/kg, a vanishingly small amount.
+
{{w|Median lethal dose|LD<sub>50</sub>}}, mentioned in the comic, is a term used in toxicology, referring to the median lethal dose, or how much of a given toxin is required to kill half of a given population (indicated by the 50 in the subscript). LD<sub>50</sub>s are usually measured in g/kg, as the amount of toxin to kill something is usually linearly related with its mass. The lower the LD<sub>50</sub>, the more lethal the toxin is. For example, the LD<sub>50</sub> for sugar is 29.7 g/kg, which is fairly high because sugar is not particularly toxic. However, {{w|Botulinum}} toxin(Commonly known as Botox), the most acutely toxic substance known, has a LD<sub>50</sub> of roughly 1 ng/kg, or 0.000000001 g/kg.
  
The comic is making the joke that the LD<sub>50</sub> of papers on toxicology is 2&nbsp;kg/kg, so it takes 2 kilograms of papers on toxicology to kill a person for each kilogram they weigh. The worldwide average weight of an adult is 62&nbsp;kg (137&nbsp;lb), so the lethal dose would be 124&nbsp;kg (273&nbsp;lb) of toxicology papers. Death is apparently caused by compression or smothering, rather than any form of toxicity.
+
The comic is making the joke that the LD<sub>50</sub> of papers on toxicology is 2 kg/kg, so it takes 2&nbsp;kilograms of papers on toxicology to kill a person for each kg he/she weighs. The average weight of a person on earth is approximately 62&nbsp;kg, so that would be 124&nbsp;kg/273&nbsp;pounds of toxicology papers.
  
The title text says it will take less paper to kill a person if the paper is shoved down their throat instead of dropped on them, either by suffocation or bursting the subject's stomach. A third method of delivering a toxin is by {{w|Subcutaneous injection|subcutaneous injections}} which are highly effective in administering vaccines and medications, but that number is omitted since they couldn't figure out how to do it. The amount of paper required to trigger a fatal blood vessel blockage would probably be fairly small if they could.
+
The title text says, it will take less paper to kill a person if the paper is shoved down their throat instead of dropped on them (either by suffocation or by bursting the subject's stomach). The third dosage usually listed is for {{w|Subcutaneous injection|subcutaneous injections}} which are highly effective in administering vaccines and medications, but that number is omitted since they couldn't figure out how to do it (if they could, the amount of paper required to trigger a fatal blood vessel blockage would probably be fairly small).
  
 
==Transcript==
 
==Transcript==
 
:[A figure in a white coat lies on the floor, crushed beneath a giant pile of binders & paper. Megan and Cueball in white coats stand next to him, looking on. Megan is holding a clipboard.]
 
:[A figure in a white coat lies on the floor, crushed beneath a giant pile of binders & paper. Megan and Cueball in white coats stand next to him, looking on. Megan is holding a clipboard.]
 
:[Caption below the panel:]
 
 
:The LD<sub>50</sub> of toxicity data is 2 kilograms per kilogram.
 
:The LD<sub>50</sub> of toxicity data is 2 kilograms per kilogram.
  
Line 24: Line 22:
 
[[Category:Comics featuring Cueball]]
 
[[Category:Comics featuring Cueball]]
 
[[Category:Chemistry]]
 
[[Category:Chemistry]]
[[Category:Multiple Cueballs]]
 

Please note that all contributions to explain xkcd may be edited, altered, or removed by other contributors. If you do not want your writing to be edited mercilessly, then do not submit it here.
You are also promising us that you wrote this yourself, or copied it from a public domain or similar free resource (see explain xkcd:Copyrights for details). Do not submit copyrighted work without permission!

To protect the wiki against automated edit spam, we kindly ask you to solve the following CAPTCHA:

Cancel | Editing help (opens in new window)