Editing 2652: Proxy Variable
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==Explanation== | ==Explanation== | ||
β | In this comic, [[Hairy]] is discussing use of a proxy variable with [[Cueball]]. In statistics, a {{w|proxy variable}} is used as a stand-in for one or more other variables that are difficult to measure. In order to be useful as such, proxy variables must be correlated with what they are intended to represent. For example, a drug might aim to reduce deaths from a slow-acting disease. But testing if it reduces deaths might take many years, so researchers might test for a proxy outcome instead, like whether the drug | + | In this comic, [[Hairy]] is discussing use of a proxy variable with [[Cueball]]. In statistics, a {{w|proxy variable}} is used as a stand-in for one or more other variables that are difficult to measure. In order to be useful as such, proxy variables must be correlated with what they are intended to represent. For example, a drug might aim to reduce deaths from a slow-acting disease. But testing if it reduces deaths might take many years, so researchers might test for a proxy outcome instead, like whether the drug reduces loss of bone density or damage to cells. Physicians use blood pressure as one of many proxies for cardiovascular health. |
Hairy is dismissing the question of whether they are studying the right variable as too expensive to answer. This is deeply ironic and thus satirical, because good {{w|experiment design}} requires sufficient attention to the robustness of all the involved parts of an experiment, even if the expense may be prohibitive. This comic might be referring to the recent discovery of [https://www.science.org/content/article/potential-fabrication-research-images-threatens-key-theory-alzheimers-disease nearly two decades] of allegedly fraudulent {{w|Alzheimer's disease}} research supporting a mistaken proxy hypothesis. | Hairy is dismissing the question of whether they are studying the right variable as too expensive to answer. This is deeply ironic and thus satirical, because good {{w|experiment design}} requires sufficient attention to the robustness of all the involved parts of an experiment, even if the expense may be prohibitive. This comic might be referring to the recent discovery of [https://www.science.org/content/article/potential-fabrication-research-images-threatens-key-theory-alzheimers-disease nearly two decades] of allegedly fraudulent {{w|Alzheimer's disease}} research supporting a mistaken proxy hypothesis. |