Difference between revisions of "2422: Vaccine Ordering"
(fixed some misspellings in the transcript, mentioned Izmir, described what a side effect is) |
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==Trivia== | ==Trivia== | ||
− | + | Originally, this comic image had no {{w|Spatial anti-aliasing|anti-aliasing}} (all its pixels wer either fully black or fully white, with no shades of gray). This gives the smooth lines a jagged appearance when the image is displayed in something other than its native size. Randall uploaded an anti-aliased version a few minutes later. | |
==Transcript== | ==Transcript== |
Revision as of 00:46, 9 February 2021
Vaccine Ordering |
Title text: You know what they say: mRNA-1273 before tozinameran, you'll have to slay a banshee in a catamaran. |
Explanation
This explanation may be incomplete or incorrect: Created by the RULER OF SMYRNA. Please mention here why this explanation isn't complete. Do NOT delete this tag too soon. If you can address this issue, please edit the page! Thanks. |
Megan is reading an article on her phone to Cueball. A report from the CDC says that it's possible to get effective immunity against COVID-19 when taking two-dose mRNA vaccine shots successively from pharmaceutical companies Pfizer and Moderna, but that this practice should not be the norm. The report in question can be viewed here; it stresses that mixing the vaccines is acceptable only in exceptional circumstances, such as "when the first-dose vaccine product cannot be determined."
Cueball wonders whether the order in which you receive the vaccines matters. Megan then attempts to create mnemonic devices to help them remember which mix-and-match strategy is best for the mRNA vaccines (e.g., "Beer before wine and you'll feel fine; wine before beer and you'll feel queer"). Megan succeeds by rhyming "Pfizer" and "wiser", but struggles with finding a rhyme for "Moderna", settling for Smyrna, an ancient city located in what is now Izmir, Turkey.
A side effect of a drug is an effect incidental to the intended purpose of the drug. Side effects can be positive or negative, though in vaccine trials the greater concern is usually about negative side effects. Becoming ruler of an ancient city that is now only a historical ruin would certainly be an odd side effect.
The title text continues the theme of difficult rhymes, using the full names of both the Moderna vaccine drug (mRNA-1273) and the Pfizer one (tozinameran).
Note: Studies have shown that the order that you have alcoholic drinks doesn't affect the severity of the hangover. The efficacy of mixing vaccines is presently unknown, an important reason why mixing them is discouraged.
Trivia
Originally, this comic image had no anti-aliasing (all its pixels wer either fully black or fully white, with no shades of gray). This gives the smooth lines a jagged appearance when the image is displayed in something other than its native size. Randall uploaded an anti-aliased version a few minutes later.
Transcript
Megan and Cueball are talking. Megan is referring to a news story on her phone.
Megan: The CDC says it's okay to mix and match the mRNA vaccines for doses 1 and 2, but only in exceptional circumstances.
Cueball: I wonder which order works better, if either.
Megan: Well you know what they say — Moderna before Pfizer, you'll be none the wiser. Pfizer before Moderna then you'll... rule ancient Smyrna.
Cueball: Weird side effect.
Megan: A lot of hard-to-rhyme drugs have those.
Discussion
Another question this suggests is whether you should wait 28 days (Moderna) or 21 days (Pfizer) between doses... JohnHawkinson (talk) 02:50, 9 February 2021 (UTC)
Can someone clarify if I, the banshee, or both need to be in the catamaran? Cwallenpoole (talk) 04:34, 9 February 2021 (UTC)
- I'd say at least the banshee needs to be in the catamaran. If only you were in it, but the banshee wasn't, you'd be slaying it from (or with, if you use the catamaran as a weapon), rather than in a catamaran. Bischoff (talk) 11:18, 9 February 2021 (UTC)
- Isn't that like the Groucho Marx joke? "I once shot an elephant in my pajamas. How it got into my pajamas, I don't know." Barmar (talk) 23:56, 9 February 2021 (UTC)
- yes -- Brettpeirce (talk) 22:34, 25 February 2021 (UTC)
- Isn't that like the Groucho Marx joke? "I once shot an elephant in my pajamas. How it got into my pajamas, I don't know." Barmar (talk) 23:56, 9 February 2021 (UTC)
quality
For those that read XKCD here first - yes, the original comic really is that low quality. I suspect Randall's going to replace it with a cleaner one at some point. 108.162.237.134 23:10, 8 February 2021 (UTC)
- Unless the low quality is intentional, some way-over-my-head joke about vaccines and mRNA, maybe? -- or the low-quality of the image as an analogy for the low-quality of the rhymes? 172.69.234.138 (talk) (please sign your comments with ~~~~)
Looks like he's uploaded a better version now. I don't know how to replace the image, though. Argis13 (talk) 23:40, 8 February 2021 (UTC)
- You can't (I just tried it). The image shown is scaled up by 2×, and the non-scaled version (the one displayed) is anti-aliased. bubblegum-talk|contribs 00:20, 9 February 2021 (UTC)
- Looks like Randall fixed it now.172.68.174.86 00:39, 9 February 2021 (UTC)
I'd like to upload the original aliased files but I don't have permission to create new pages.
The original 1x version is here and the 2x version, still aliased but with 4 pixels of #f7f7f7, is here Landfillbaby (talk) 01:21, 9 February 2021 (UTC)
I see the right one now162.158.187.161 15:03, 9 February 2021 (UTC)
"Pfizer before moderna, that'll learn ya" - Alex Booker on Last Leg (UK channel 4) 5th Feb.
162.158.2.226 17:37, 9 February 2021 (UTC)
EDIT: Comment was deleted due to spamming-ish-ness.