Difference between revisions of "2446: Spike Proteins"
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==Transcript== | ==Transcript== | ||
− | + | :[Cueball is seated at a desk with an open laptop in front of him. Megan stands behind Cueball. Beret Guy is in front of the desk, walking away and looking back at the two.] | |
+ | :Beret Guy: Got the vaccine! | ||
+ | :Megan: Congrats! | ||
+ | :Beret Guy: Time to go make some spike proteins. | ||
+ | |||
+ | :[Beat panel with only Cueball and Megan present.] | ||
+ | |||
+ | :[Panel with only Beret Guy, walking back towards the desk. He is carrying a huge wad of material shaped like a spike protein but at least a few feet long.] | ||
+ | :Beret Guy: Ok! Here's my first try. | ||
+ | |||
+ | :[Beret Guy plops the 'spike protein' onto Cueball's desk. Half of it takes up the entire desk area not covered by the laptop, while the other half overhangs the desk. Cueball is grabbing the lid and base of his laptop with both hands, pulling it partially closed and away from the spike protein.] | ||
+ | :''Plop'' | ||
+ | |||
+ | :[Beret Guy turns to leave the panel with an outstretched finger pointing skyward. The overhanging part of the spike protein has sagged, and it is dripping some wet material over both the floor and desk.] | ||
+ | :Beret Guy: ''More!'' | ||
+ | :Cueball: Ewww. | ||
+ | :Megan: Why is it so ''wet??'' | ||
{{comic discussion}} | {{comic discussion}} |
Revision as of 00:40, 6 April 2021
Spike Proteins |
![]() Title text: Ugh, it's stuck to my laptop. It must have bound to the ACER-2 receptor. |
Explanation
![]() |
This explanation may be incomplete or incorrect: Created by a SPIKE PROTEIN. Please mention here why this explanation isn't complete. Do NOT delete this tag too soon. If you can address this issue, please edit the page! Thanks. |
This is another comic about the current vaccine against COVID-19. A vaccine is designed to provoke an immune response from the body of the recipient, part of which is the creation of spike proteins that are intended to disable the perceived pathogen.
Beret Guy, in his usual fashion, misunderstands how reality works, then reality alters to fit his view of it. After receiving the vaccine, he (not his immune system) builds the spike protein, which is many, many orders of magnitude larger than a real spike protein, and places it on the desk where Cueball and Megan are working, rather than retaining it in his body where it would be effective, if it were a normal spike protein. This is unusual, as when the body naturally makes a spike protein, they are made in small amounts to be distributed throughout the body. When Beret Guy makes it, he makes a large, damp wad through unknown means. This provokes an understandable response of both disgust and confusion from the two.
Beret Guy then leaves, with the intention of making more, better spike proteins, though it is unclear what he would consider "better."
The title text is a pun on ACER, a brand of computers including laptops, and the ACE2 receptor, an entry point on a cell to which the SARS-COV-2 virus attaches during the process of entering the cell. [1]
It is notable that ACER2 is a real enzyme in humans. This is probably a coincidence.
Transcript
- [Cueball is seated at a desk with an open laptop in front of him. Megan stands behind Cueball. Beret Guy is in front of the desk, walking away and looking back at the two.]
- Beret Guy: Got the vaccine!
- Megan: Congrats!
- Beret Guy: Time to go make some spike proteins.
- [Beat panel with only Cueball and Megan present.]
- [Panel with only Beret Guy, walking back towards the desk. He is carrying a huge wad of material shaped like a spike protein but at least a few feet long.]
- Beret Guy: Ok! Here's my first try.
- [Beret Guy plops the 'spike protein' onto Cueball's desk. Half of it takes up the entire desk area not covered by the laptop, while the other half overhangs the desk. Cueball is grabbing the lid and base of his laptop with both hands, pulling it partially closed and away from the spike protein.]
- Plop
- [Beret Guy turns to leave the panel with an outstretched finger pointing skyward. The overhanging part of the spike protein has sagged, and it is dripping some wet material over both the floor and desk.]
- Beret Guy: More!
- Cueball: Ewww.
- Megan: Why is it so wet??
![comment.png](/wiki/images/0/03/comment.png)
![comment.png](/wiki/images/0/03/comment.png)
![Icons-mini-action refresh blue.gif](/wiki/images/e/e5/Icons-mini-action_refresh_blue.gif)
Discussion
I got my 1st dose today. My apartment is swarming with spike proteins. Barmar (talk) 01:17, 6 April 2021 (UTC)
- My Dad got his second dose on Thursday & got allll the usual symptoms. He's not on antibiotics, but his breath smells like the taste of antibiotics to me. I swear, dogs aren't the only ones that can smell a body's reaction to coronavirus (and also, for reference, cancer stinks).
- ProphetZarquon (talk) 16:39, 6 April 2021 (UTC)
Can someone here create a "COVID-19 vaccine" category (as a subcategory of COVID-19)? Randall has been posting a lot of vaccine-related comics recently. 172.69.35.113 02:11, 6 April 2021 (UTC)
- Done Category:COVID-19 vaccine. Please add more if I missed some earlier ones. --Kynde (talk) 14:23, 7 April 2021 (UTC)
I don't think the description as it is right now is very accurate. It seems to be stating that the spike protein is a normal protein normally produced by humans, rather than a protein used by SARS-CoV-2 (and likely other similar viruses (virii?) to aid in their infection. In this case, beret guy has gotten an MRNA vaccine (either Moderna or Pfizer), so has given his cells the recipe to make this spike protein for themselves, until the immune system realizes it shouldn't be there. PotatoGod (talk) 07:08, 6 April 2021 (UTC)
- PotatoGod, The J&J vaccine also would've given his cells the recipe to make the spike protein. It just uses an adenovirus to deliver DNA into your cells, where the cells convert it into mRNA and then use that to make the spike proteins. Ahecht (talk) 19:29, 7 April 2021 (UTC)
I'm a bit suprised there was no Ever Given comic... 162.158.111.161 13:45, 6 April 2021 (UTC)
- It's been delayed by two weeks, by having been sent round Africa...
- (Srsly, though, if the sufficient dose of inspiration hasn't happened - and it's not his usual geek-out topic - then it's no more likely to be mentioned than (say) Brexit issues seriously messing with exports, especially of foodstuffs. And I think the US is largely proof from Suez (or Channel) cargo movements, so may not be on the radar. Chip shortages, etc, are likely from C19 disruptions, not from the otherwise unaffected trans-Pacific shipping.) 162.158.159.108 22:28, 6 April 2021 (UTC)
- Just thought that the event itself is big and interesting enough to warrant a comic, even if it doesn't influence US as much as Europe. (Good joke, though!) 141.101.104.81 10:48, 7 April 2021 (UTC)
As a new 'image' of the Corona virus has recently been used in a scientific publication (as discussed in https://www.snopes.com/fact-check/moist-coronavirus-image/ ), showing a 'moist' Corona virus, I got the impression that the "Why is it so wet?" part of the comic refers to this. (Otherwise it seems like a remark coming out of nowhere.) Of course, at the normal scale of a virus, 'wet' and 'dry' don't really mean anything, but as 'images' of the virus are mostly artistic representations anyway, there's no reason not to show them as 'moist'. (Unsigned addition by 162.158.92.102)
- That article has the odd assertion that "it’s important to remember that art is objective." I think they mean "subjective". BunsenH (talk) 17:25, 6 April 2021 (UTC)
- I subject to such a misuse of terms! 141.101.98.218 22:31, 6 April 2021 (UTC)
EDIT: Removed annoying tag. Sorry! {)|(}Quill{)|(} 18:15, 6 April 2021 (UTC)
- It's marked as "incomplete" because it's new and still under active revision. I don't know if there's a formal criterion set down anywhere, but I don't think it would be appropriate to remove that tag from any page that's been repeatedly edited in the previous ten days or so. BunsenH (talk) 18:33, 6 April 2021 (UTC) EDIT: I find it especially eyebrow-raising when someone edits a page and removes that tag at the same time. If I edit a page, I want at least one more pair of eyeballs to check what I've done. As opposed to the implied "Now that I have made my changes, the page is in its final form."
- Agree with the above user. This text is always placed when a comic is new and is not usually removed for a few days (or even longer). Also, although you say that "this is not spamming", it feels like spamming if you place this exact same text on multiple comics, without even having a real discussion on why a comic is incomplete. 172.69.33.249 22:59, 6 April 2021 (UTC)
- Yes please do not use that template you have made! It is a very bad idea! --Kynde (talk) 08:04, 7 April 2021 (UTC)
- Sorry. I will delete the template and topics. {)|(}Quill{)|(} RE-SIGNED 14:02, 29 April 2021 (UTC)
- Apologies, I somehow managed to add this to the category of pages marked for deletion via my obsolete Date template, which I signed that comment with. My bad! {)|(}Quill{)|(} 14:02, 29 April 2021 (UTC)
- Sorry. I will delete the template and topics. {)|(}Quill{)|(} RE-SIGNED 14:02, 29 April 2021 (UTC)
- Yes please do not use that template you have made! It is a very bad idea! --Kynde (talk) 08:04, 7 April 2021 (UTC)
- Agree with the above user. This text is always placed when a comic is new and is not usually removed for a few days (or even longer). Also, although you say that "this is not spamming", it feels like spamming if you place this exact same text on multiple comics, without even having a real discussion on why a comic is incomplete. 172.69.33.249 22:59, 6 April 2021 (UTC)
- Beret Guy superpowers?
Sorry, I don't know if this is the right format for this, but it seems that not only does Beret Guy often misunderstand, he also has superpowers. Making a life-sized spike protein would classify as that to me. Djbrasier (talk) 01:28, 7 April 2021 (UTC)
- Yes I have added this already. I made this category long time ago: Category:Strange powers of Beret Guy. --Kynde (talk) 07:53, 7 April 2021 (UTC)
- Would the eating of nuts-the machine part-be counted? I’m talking about 452: Mission. 42.book.addict (talk) 21:07, 2 February 2024 (UTC)
Can't help but wonder if this is a masturbation joke
- Not any more than any other random statement.Jkshapiro (talk) 15:59, 13 March 2022 (UTC)
- It all depends upon how you try to pull it off. 172.70.162.155 20:21, 13 March 2022 (UTC)